High Performance Liquid Chromatography is used in many industries including in the pharmaceutical, food, cosmetic, and the environmental sectors. The history of HPLC begins with the invention of chromatography itself, just after the turn of the 20th century. It has since evolved to become the liquid chromatography we know and use today. If you’re hoping to work with testing in the pharmaceutical industry, you may be interested to know the history of how HPLC came to be. Interestingly, many of the developments along HPLC’s journey came from industry professionals and not from university researchers or professors. Read on to learn.. READ MORE »
Who doesn’t love Aspirin? It’s a common drug can treat pain, fevers and inflammation. In low doses, it can even prevent heart attacks, strokes and blood clotting. As a result, it is no surprise that many major pharmaceutical companies offer their own version of the drug. Last week at AAPS, instructor Jason Chu led a lab session where students were taught how to conduct various laboratory tests on Aspirin in an effort to evaluate various properties such as; product purity, identity, safety and quality. These pharmaceutical tests are useful because they provide students with technical skills that are required.. READ MORE »
Laboratory mice are small rodents of the species Mus Musculus that are typically bred and kept for scientific research. Lab mice have long been the species of choice in the study of human diseases; in fact, they are typically the first to partake in a lot of preclinical research. However, recently researchers have reported that the model of the lab mouse has actually been misleading in the research of at least three major diseases and ailments, including sepsis, trauma, tuberculosis, cancer and heart disease. If you plan on enrolling in clinical research courses, or if you have recently started your.. READ MORE »
Dating back to ancient Mesopotamia, humans have enjoyed the making and drinking of wine. The health benefits of wine – particularly the red variety – have been praised by everyone from scientists to sommeliers, reinforcing the common belief that a little red wine each day is actually good for our bodies. Clinical research on the subject has been rich and varied, featuring investigations into wine’s potential to protect against depression, breast cancer, the signs of aging, liver disease – and even sunburn! And now, a new study has emerged linking wine consumption with protection against cardiovascular disease (CVD), a condition.. READ MORE »
It’s quite widely accepted that an aspirin a day can keep heart attack and stroke at bay. But how does it work? Aspirin interferes with your blood’s clotting action. When you bleed, your blood’s clotting cells, called platelets, build up at the site of your wound. The platelets help form a plug that seals the opening in your blood vessel to stop bleeding. But when clotting happens where it shouldn’t – like in the vessels that supply your heart with blood – an artery could get blocked, which would result in a heart attack. A daily aspirin can help keep.. READ MORE »
It’s old news that a balanced diet – one that includes fruits and vegetables – is the key to sustaining good health. But how much is enough? Balanced for one person might mean a forkful of broccoli and a handful of grapes. For others, the pursuit of healthy eating means juicing an entire kale, three apples and a whole head of spinach – and downing it all before breakfast. But new clinical research from China and the United States has revealed then when it comes to optimizing our intake of those powerful micronutrients, five is the magic number. Tests confirm.. READ MORE »
Novartis will collaborate with Google to offer patients the new Smart Lens, an ocular device that uses miniature electronics to help the eye focus better, and can also measure the body’s glucose levels by analyzing tears.
Wearable health-tracking technology is changing the way trial researchers collect and analyze big data, transforming test subjects into active research collaborators and widening the scope of clinical research.
Last year, Japanese whistleblowers exposed the falsification of trial data for Diovan – Novartis’ blockbuster blood pressure drug. Ultimately, the ensuing investigation led to the arrest of one man, Nobuo Shirahashi, who was accused of manipulating the Diovan data and skewing the clinical research published by two Japanese universities. Last month, Shirahashi was detained for questioning and then recently re-arrested only days ago as more evidence emerged to link him to the falsified test results. Now, it seems both Novartis and its ex-employee with face criminal charges for misleading consumers about the range of Diovan’s therapeutic powers. Exaggerated Claims Novartis’.. READ MORE »
It seems that alternative applications for diabetes drugs are popping up all over the place. We recently discussed clinical research out of Belgium that revealed the unexpected anti-aging properties of metformin – the world’s most used diabetes medication. It actually toughens up cells so they stay stronger and live longer, keeping the signs of aging at bay. And now, at a recent meeting of the Endocrine Society in Chicago, researcher Dr. F. Xavier Pi-Sunyer announced that a different type 2 diabetes treatment called Liraglutide not only promotes weight loss, but also reverses the course of pre-diabetes. Competitive Results The study.. READ MORE »